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Genuine opportunities for career and personal development, Modern “smart office” locations providing agile & collaborative workspaces, Dynamic international working environment, Attractive additional benefits

We are looking for a to lead the roadmap and implementation of the company in silico strategy and its integration to Next Generation Risk Assessment (NGRA) and work hand by hand with team specialists in Chemical Risk Assessment, PBPK and other computational approaches. In addition, you will provide scientific risk assessment expertise to Nestlé R&D projects from inception through all stages of development (Safety by Design) with emphasis on computational toxicology applications for strategies considering in silico new approach methodologies (waiving, read-across, in silico predictions, molecular dynamics simulation and Off-target binding identification) for risk assessment and the integration of in vitro and in silico methodologies for NGRA

Aside from this, you will research on strategies to speed up and improve chemical safety-based decision making and to inform risk management. Also, you will provide technical support to operations to manage food safety issues

A Day in the Life of a Senior Specialist in Computational Toxicology

• Support the development and refine NGRA framework to assess the safety of Nestlé products (including e.g., novel ingredients) and mixtures lacking toxicological data
• Lead the development and application of computational chemistry approaches to analyze data from high throughput in vitro assays, data from in vivo toxicity studies, chemical properties, and other relevant sources to develop predictive models for toxicity and physicochemical properties in applications for screening for the potential human health effects of chemicals
• Develop/implement new approaches in Risk Assessment, to support R&D projects and management of issues in operations. Demonstrate widely recognized competences in in silico toxicology and its application in food risk assessment
• Lead the roadmap and implementation of the in silico strategy and its integration to NGRA
• Lead projects, project streams and safety relevant activities in new product development projects (NR, NPTCs and R&D centers). This includes the planning, management and interpretation of externally contracted activities
• Provide evaluations and propose strategies for molecules (from new ingredients, food contact materials, contaminants, plant toxins) without toxicological data in response to operational issues, crisis and Early Warning
• Develop and integrate key knowledge area and expertise into business
• Develop tools in the domain of food risk assessment through research projects and contributions to expert groups

What will make you successful

• PhD in Natural Sciences/Toxicology- or Chemo-informatics, Postdoc(s) would be an asset
• Profound knowledge and experience in research and application of computational toxicology tools to support the risk assessment of chemicals in food
• Experience in toxicology in the context of RD
• Experience in risk assessment of chemicals and bioactive compounds in foods and other areas (packaging, chemical contaminants, supplements, new ingredients), and integration of in vitro/in silico approaches
• Previous exposure to alternatives to animal testing (in vitro/in silico approaches)
• Experience in contributing/chairing international expert groups
• Strength in communication (written and oral), collaboration/cooperation and networking. Coaching of junior colleagues
• Good written and oral communication in English
• Nestlé is committed to the accessibility of its recruitment process. If you require an adaptation during the recruitment process, please do let us know so we can support you effectively. All information will be treated confidentially
• At Nestlé, we want to help shape a better and healthier world, inspire people to live healthier lives and deliver impact at a scale and pace that makes a difference. We do this by fostering a diverse, friendly, supportive, and collaborative environment, that creates positive disruption, embraces innovation, and empowers people and teams to win. We aim to hire friendly, respectful, inspiring people who care about the people’s lives that we touch every single day

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