Sophia Genetics SA

Are you a Bioinformatician who’s eager to learn and contribute to team goals, no matter the scope or nature of the task? Do you thrive in fast-paced, dynamic environments and adapt easily to shifting business priorities? If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Pipeline Development Team as our Bioinformatician, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide. This role is a hybrid opportunity, requiring 3 days onsite our corporate office in Rolle, CH. Our Mission We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe. Your Mission As our Bioinformatician, you will contribute to the development, optimization, and scaling of tools and algorithms that support variant calling and clinical interpretation of genomic data, helping us deliver precision diagnostics at scale. Please note: this role does not involve machine learning development. The vale you bring Contribute to develop, test and document tools and algorithms for the detection and annotation of genomic variants. Contribute to improve the efficiency, reproducibility, and scalability of our development processes. Contribute to expand the testing and documentation coverage of existing tools and algorithms. Requirements Masters in Bioinformatics, Computational Biology, Human Genetics, or a related field, with relevant experience in data analysis and/or algorithm development. Proficient in Python, Git, and Bash. Proficiency in C++ or R is a plus Experience with high-performance computing (HPC) environments, bioinformatics workflows, parallelization, and containerization (e.g., Docker). Experience with NGS data analysis is a plus Experience with modern software development practices, including CI/CD, unit testing, code reviews, and reproducible research principles. Effective communication and collaboration skills in a multicultural and interdisciplinary environment. Willingness to be coached and learn from more experienced members of the team. Comfortable working in a fast-paced, dynamic setting, with the flexibility to adapt to shifting business priorities. Benefits You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth. Business recognition and accolades include: World’s most innovative companies (Top 10) World’s smartest companies (Top 50) 100 Best Places to Work in Boston Top 10 European Tech Startup Top 10 European biotechs startup to watch Top 25 East-Coast Biotech to watch Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview: Sickness and Accident coverage through Helsana Meal Vouchers at 90CHF PM with our partner cafeteria A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit Free parking in an easy to access location A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding As our global HQ, you’ll have direct interaction and exposure to senior leadership and our executive team locally Our DNA Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous Our Virtues At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We decide; We do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal The Process Apply now with your CV and any supporting information. Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business. If you need additional support for accessibility, please contact our TA team for assistance. We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilize agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please. Start Date: ASAP Location: Rolle, CH Contract: Temporary, 12 Month Contract

Are you a commercially astute accountant with expertise in GL or Cost Accounting? Have you worked within an international or publicly listed organisation? If this sounds like you and you are driven by purpose, Join the SOPHiA GENETICS Finance Team Team as a General Ledger Accountant, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide. Enjoy the flexibility of a hybrid work schedule allowing 2 days PW home working, connected to our corporate office in Rolle, Switzerland. Our mission We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe. Your mission Reporting to the Director, Accounting you will play a key role in general ledger accounting, helping ensure compliance with internal controls and SOX Requirements. The value you bring: Perform monthly, quarterly and annual GL Closing activities in accordance with IFRS & Local GAAP. Ensure compliance with internal control and SOX documentation requirements, maintaining accurate and up-to-date process documentation. Work with relevant stakeholders to enhance the structure and accuracy of financial data in the ERP system. Provide ad hoc support for standard cost calculation, updates, and analysis. Collaborate with the FP&A team to analyze production variances and cost drivers. Requirements We know that every background is different, but to be best set for success we see you bringing: 2-4 Years of experience in financial audit, public accounting or similar corporate accounting role Direct working knowledge within an international or publicly listed organisation is highly valued, with an understanding of multi-entity finance & accounting. Solid understanding of general accounting principles, internal controls, international standards and SOX. Exposure to cost accounting principles is an advantage As a public organisation facing ongoing commercial growth, you will bring a success-orientated and solutions-focused mindset that embraces team collaborations, change, growth and inclusion. As an international organisation, English is our primary business language and you will need to bring full fluency in English. As part of your recruitment journey, you should expect to meet English-only speakers, so for best chances of success, you should include your CV in English. Non-English CVs have a high likelihood of being rejected at application stage. Benefits You will be joining an organisation with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth. Business recognition and accolades include: World's most innovative companies (Top 10) World's smartest companies (Top 50) 100 Best Places to Work in Boston Top 10 European Tech Startup Top 10 European biotechs startup to watch Top 25 East-Coast Biotech to watch Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview: Sickness and Accident coverage through Helsana Meal Vouchers at 90CHF PM with our partner cafeteria A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit Free parking in an easy to access location A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding As our global HQ, you’ll have direct interaction and exposure to senior leadership and our executive team locally Our DNA Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous Our Virtues At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn. At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal The process We use the power of AI to help our partners make decisions. If you’re utilising AI in your search and application process, why not use some of these prompts: ‘What impact can I expect to have on the world by working at SOPHiA GENETICS?’ ‘I have an interview with SOPHiA GENETICS. What should I know before I meet with them?’ ‘I am a *job title* - What can SOPHiA GENETICS offer my career?’ Apply now with your CV and any supporting information. Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business. If you need additional support for accessibility, please contact our TA team for assistance. We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilise agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please. Starting Date: ASAP Location: Rolle, CH (Office-Hybrid) Contract: Permanent, Full-time

Do you bring hands on experience in the NGS wet lab, coupled with experience managing technical teams? Have you worked closely with sales, FAS or commercial teams or external customers to achieve commercial objectives? If this sounds like you and you are driven by purpose, Join the SOPHiA GENETICS FAS Team as a Field Application Scientist Manager, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide. Ideally, you will be in proximity to our Rolle Corporate office on a hybrid work-schedule, enabling you to connect seamlessly with colleagues and still benefit from the flexibility of home working. Our Mission We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe. Your Mission Reporting to the VP Customer Experience, as FAS Manager you will be responsible for leading a global team of Field Application Specialists (FAS) dedicated to Next-Generation Sequencing (NGS) technologies. You will ensure technical support for our clients, optimize wet lab processes, and resolve complex field-based issues. The value you bring Manage and oversee a global team of FAS specializing in NGS, ensuring the achievement of technical and commercial objectives. Provide advanced technical support to clients, including troubleshooting and optimizationimplementation of experimental protocols. Collaborate closely with sales and Product Management teams to identify customer needs. Actively participate in deployment, validation, and training phases at client sites to guarantee high satisfaction levels. Analyze team performance, monitor KPIs, and implement continuous improvement plans. Requirements We know that every background is different, but to be best set for success we see you bringing: Proven experience (at least 5 years) in a laboratory setting (wet lab) working with Next-Generation Sequencing (NGS) technologies. Minimum of 3 years of experience in managing a technical team (FAS, technical support, or laboratory team). Expertise in NGS experimental protocols (library preparation and targeted enrichment by capture, sequencing, data analysis). Experience with liquid handler robotics (Hamilton, Beckman etc) is highly advantageous Previous exposure to a commercialised environment, with a track record of providing support to customers or enabling commercial objectives Managing a global field team will involve travel. As a public organisation facing ongoing commercial growth, you will bring a success-orientated and solutions-focused mindset that embraces team collaborations, change, growth and inclusion. As an international organisation, English is our primary business language and you will need to bring full fluency in English. As part of your recruitment journey, you should expect to meet English-only speakers, so for best chances of success, you should include your CV in English. Non-English CVs have a high likelihood of being rejected at application stage. Benefits You will be joining an organisation with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth. Business recognition and accolades include: World's most innovative companies (Top 10) World's smartest companies (Top 50) 100 Best Places to Work in Boston Top 10 European Tech Startup Top 10 European biotechs startup to watch Top 25 East-Coast Biotech to watch Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview: Switzerland Sickness and Accident coverage through Helsana Meal Vouchers at 90CHF PM with our partner cafeteria A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit Free parking in an easy to access location A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding As our global HQ, you’ll have direct interaction and exposure to senior leadership and our executive team locally Our DNA Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous Our Virtues At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn. At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal The process We use the power of AI to help our partners make decisions. If you’re utilising AI in your search and application process, why not use some of these prompts: ‘What impact can I expect to have on the world by working at SOPHiA GENETICS?’ ‘I have an interview with SOPHiA GENETICS. What should I know before I meet with them?’ ‘I am a *job title* - What can SOPHiA GENETICS offer my career?’ Apply now with your CV and any supporting information. Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business. If you need additional support for accessibility, please contact our TA team for assistance. We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilise agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please. Starting Date: ASAP Location: Rolle, CH Contract: Permanent

Are you an experienced Bioinformatician with strong project leadership skills and the ability to independently drive complex initiatives? Do you thrive in fast-paced, dynamic environments and adapt easily to shifting business priorities? If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Tertiary Development Team as our Expert Bioinformatician, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide. This role is a hybrid opportunity, requiring 3 days onsite our corporate office in Rolle, CH. Our Mission We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe. Your Mission As our Expert Bioinformatician, you will lead the development, optimization, and scaling of tools and algorithms that enable the clinical interpretation of genomic data, playing a key role in delivering precision diagnostics at scale (note: this role does not involve machine learning development). The vale you bring Design, develop, and maintain robust, scalable tools and algorithms for genomic annotation and variant interpretation. Drive initiatives to enhance the efficiency, reproducibility, and scalability of our development processes. Lead efforts to strengthen code testing frameworks and documentation standards, ensuring compliance with internal and external quality requirements. Act as the primary liaison between the Tertiary Development team and other cross-functional teams (e.g., pipeline development, TECH, clinical affairs, software engineering) to coordinate deliverables. Provide regular project updates and technical insights to the Director of Pipeline Development and the executive leadership team. Requirements PhD in Bioinformatics, Computational Biology, Human Genetics, or a related field, with relevant industry or postdoctoral experience. Proficient in Python, SQL, Git, and Bash. Proficiency in C++ or R is a plus. Extensive experience with high-performance computing (HPC) environments, bioinformatics workflows, parallelization, and containerization (e.g., Docker). Experience with NGS data analysis is a plus. Demonstrated knowledge of annotation, and interpretation of germline and somatic variants in human genomes. Strong grasp of modern software development practices, including CI/CD, unit testing, code reviews, and reproducible research principles. Strong project leadership and cross-functional coordination skills, with a proven ability to drive complex projects independently. Effective communication and collaboration skills in a multicultural and interdisciplinary environment. Comfortable working in a fast-paced, dynamic setting, with the flexibility to adapt to shifting business priorities. Benefits You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth. Business recognition and accolades include: World's most innovative companies (Top 10) World's smartest companies (Top 50) 100 Best Places to Work in Boston (2022-2025) Top 10 European Tech Startup Top 10 European biotechs startup to watch Top 25 East-Coast Biotech to watch Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview: Sickness and Accident coverage through Helsana Meal Vouchers at 90CHF PM with our partner cafeteria A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit Free parking in an easy to access location A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding As our global HQ, you’ll have direct interaction and exposure to senior leadership and our executive team locally Our DNA Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous Our Virtues At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn. At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal Starting Date: ASAP Location: Rolle, Switzerland - (Hybrid, 3 Days Per Week) Contract: Permanent

Do you enjoy leveraging your technical expertise in NGS and liquid handling robots to build credibility and deliver valuable insights to customers? Are you passionate about traveling to customer sites to lead trainings and provide hands-on support? If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Genomic Research team as our Field Application Specialist, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide. This is a field-based role, and you will spend up to 50% of your rime orking across the European territory supporting customers. We are prioritizing canddates in proximity to our Rolle, CH Headquarters to facilitate efficient collaboration with colleagues, and will support relocation for suitably experienced individuals. Our mission We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe. Your mission As our Field Application Specialist you will be responsible for training and supporting our customers on all SOPHiA GENETICS Bundle solutions. You will closely interact with the sales and product management teams to relay customer needs and feedback, ensuring we continuously improve our offerings. You will also contribute to ongoing laboratory projects, such as protocol optimizations, and support the team by drafting scientific and quality documents, including fact sheets and work instructions. The vale you bring Customer Training and Support: Provide appropriate training to customers on SOPHiA GENETICS solutions, manage customer support Build effective relationships with new and existing clients for field application purpose, monitor the customer feedback on product usage Internal Laboratory participation: Elaborate laboratory documents Train internal and external collaborators Product Development: Gather feedback from customers regarding their needs, communicate internally for product design improvement Coordinate with the development and/or marketing team for proper market implementation Requirements We know that every background is different, but to be best set for success we see you bringing: Hands on experience with NGS library preparation and capture This role may suit a first-mover from the lab, but you'll ideally already bring previous customer facing exposure in an FAS or implementation style role Experience with automation or liquid handling robotics (Hamilton, Revvit, Beckman, Eppendorf) extremely valuable An ability to travel to various locations across Europe to execute training and any customer support You will need to be full fluent in English - Additional European language skills beneficial. Benefits You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth. Business recognition and accolades include: World's most innovative companies (Top 10) World's smartest companies (Top 50) 100 Best Places to Work in Boston Top 10 European Tech Startup Top 10 European biotechs startup to watch Top 25 East-Coast Biotech to watch Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview: Sickness and Accident coverage through Helsana Meal Vouchers at 90CHF PM with our partner cafeteria Free coffee, fruit and snacks As part of our flagship corporate office, you'll have in-person access to our strong agenda of social activities, in-person townhalls, kick-off and mid-year events Our DNA Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous Our virtues At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn. At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal The process We use the power of AI to help our partners make decisions. If you’re utilizing AI in your search and application process, why not use some of these prompts: ‘What impact can I expect to have on the world by working at SOPHiA GENETICS?’ ‘I have an interview with SOPHiA GENETICS. What should I know before I meet with them?’ ‘I am a *job title* - What can SOPHiA GENETICS offer my career?’ Apply now with your CV and any supporting information. Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business. If you need additional support for accessibility, please contact our TA team for assistance. We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilize agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please. Starting Date: ASAP Location: Rolle, CH and MUST be open to travelling 50% of the time. Contract: Permanent