ETH Zurich

PhD position in Organic Chemistry/Radiochemistry 100%, Zurich, fixed-term print Drucken The Center for Radiopharmaceutical Sciences (CRS) at ETH Zurich develops new innovative radiolabelled pharmaceuticals for diagnosis and therapy. It offers state of the art infrastructure and equipment to perform research from -bench-to-bedside-. Project background Radiopharmaceuticals are important molecular probes for the non-invasive detection of diseases with very high sensitivity. At the CRS we are developing and testing novel 18F-labelled radiopharmaceuticals for the detection of neurodegeneration, cardiovascular diseases and cancer. To achieve this goal, we also investigate novel chemistry and radiolabelling protocols. Job description The mission of our multidisciplinary research focus in organic chemistry and radiochemistry is to develop innovative fluorine-18 radiochemistry for medicine. You will be responsible for exploring novel chemistry in the cold lab, in particular the investigation of novel fluorination methods/reagents and the synthesis of precursors for radiolabelling. Furthermore, you will get trained for performing independently 18F-radiolabelling experiments in the HCI Isotope Labs. Additionally, you will also be involved in teaching by supervising practical laboratory courses and bachelor/master theses. Profile Essential: A Master's degree in Chemistry Experience in organic synthesis and/or methodology development Excellent communication skills in English Desirable: Experience in radiochemistry Key personal characteristics: Driven by curiosity and be an enthusiastic, dedicated and creative individual Commitment to actively participate and promote a positive lab environment Workplace Workplace We offer Access to state-of-the-art facilities, equipment, and resources at ETH Zurich An open and supportive research environment Career development under direct mentorship Fully funded position chevron_right Working, teaching and research at ETH Zurich We value diversity In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Curious? So are we. We look forward to receiving your online application with the following documents: Motivation letter (max. 1 page) Curriculum Vitae Academic transcripts (Bachelor and Master) Names and contact details of 1-2 references Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered. Further information about the Center for Radiopharmaceutical Sciences can be found on our website. Questions regarding the position should be directed to Dr. Stefan Gruber, Tel +41 44 633 68 94 or email stefan.gruber@pharma.ethz.ch (no applications). About ETH Zürich ETH Zurich is one of the world-s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.

Postdoc on Digital Market Regulation 100%, Zurich, fixed-term print Drucken The groups of Prof. Stefan Bechtold at the Center for Law & Economics at ETH Zurich and Prof. Christian Peukert at the Digital Markets Lab at HEC Lausanne conduct a multi-year project funded by the Swiss National Science Foundation on the regulation of digital markets. For this project, we are soliciting applications for a postdoc. Project background In this empirical project, we combine the perspectives of management, economics, law, and computer science to study how regulatory frameworks in digital markets are enforced and how firms respond to such regulation. We are interested in policy questions of data, privacy, competition, intellectual property, content moderation, AI governance and related fields. We develop new tools for measuring regulatory effectiveness in the digital economy, focusing on key issues such as how platforms collect and use personal data, how firms lobby for favorable regulations, and what effect privacy laws in different regions have. We also analyze the influence of regulations on online competition and content diversity, studying how antitrust laws and copyright enforcement shape market dynamics. Job description As a postdoc in this project, you conduct empirical research in the areas mentioned above, both as a lead author and collaborator. You will be able to pursue your research agenda in a very research-focused environment at leading research universities, with limited teaching or organizational obligations. We offer a truly interdisciplinary environment at the intersection of economics, law, management science, computer science, and law. We provide close supervision, guidance, time and resources for you to develop as a new scholar in the field. Profile You have a PhD in economics, computer science, management science, law or a related field You are excited to join an international and interdisciplinary group that spans many topics and fields You feel that your enthusiasm, skills, and creativity provide you with a sound basis to start an academic career Workplace Workplace We offer This position will lead to either an employment at ETH Zurich (primary workplace in Zurich) or at HEC Lausanne (primary workplace in Lausanne). We offer a truly interdisciplinary working environment with a long-standing collaboration between ETH Zurich and HEC Lausanne. We maintain close contact with leading scholars in our fields across the globe, including at top U.S. institutions. Throughout the year, we organize various seminar series and conferences. These events create rich opportunities for you to meet and exchange ideas with discourse-shaping researchers in your field . Our broad network opens attractive career prospects. We offer an internationally competitive salary and comprehensive benefits. In addition, we provide support for attending multinational conferences and workshops as well as research stays abroad. We envision a starting date in the summer or fall of 2025, but are flexible. The intitial employment runs for two years, with the possibility of extensions. chevron_right Working, teaching and research at ETH Zurich We value diversity In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Curious? So are we. We look forward to receiving your online application with the following documents: a cover letter (2 pages max) your CV your university transcript with grades short description of your research interests (3 pages max) list of 2-3 references Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered. We will review applications on a rolling basis. Please submit your application at your earliest convenience, but not later than January 15, 2025. Do you have questions? Please reach out to Prof. Stefan Bechtold (sbechtold@ethz.ch) or Prof. Christian Peukert (christian.peukert@unil.ch). About ETH Zürich ETH Zurich is one of the world-s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.

PhD Position on Soil Biogeochemical Dynamics of Alpine Catchments 100%, Zurich, fixed-term print Drucken We seek a PhD student to study the effects of soil redistribution on biogeochemical fluxes as well as carbon and nutrient storage in Swiss alpine catchments with contrasting geological background. This position is integral to an interdisciplinary research team, which includes 3 PhD students across groups at ETH Zurich and EPF Lausanne. Project background Mountain regions are hotspots of contemporary environmental change where the interactions between climate, parent material, topography, and biota create key ecosystem services related to the cycling and storage of carbon in soil. Yet, our ability to quantify and predict soil carbon stocks and lateral fluxes across such highly heterogeneous landscapes is still limited. By integrating field monitoring, soil biogeochemical analysis, and numerical modeling of coupled ecohydrological and geomorphological processes, we will evaluate the dynamics of lateral soil carbon redistribution across environmentally complex and geochemically distinct landscapes. The advertised position is part of a multidisciplinary SNSF-funded project that is motivated by the urgent need for a better understanding of biogeochemical fluxes in alpine catchments where eco-hydrological conditions are changing rapidly due to climate change. The project is a joint collaboration between EPFL (Sara Bonnetti), ETH Zürich (ETHZ, Sebastian Doetterl), University of Lausanne (UNIL, Stuart Lane, Nadav Peleg), and the Swiss Federal Institute for Forest, Snow and Landscape Research (WSL, Katrin Meusburger), with a team encompassing (eco)hydrologists, soil scientists, and geomorphologists. Job description The PhD student will be responsible for the soil physical and biogeochemical characterization of soils at the catchment scale and assess erosional soil fluxes using radionuclide assessment approaches, with the specific duties: Participate in the setup and maintenance of field soil and plant sampling Assess soil fluxes Analyze soil organic matter sources, quality and stabilization Determine shifts in soil nutrient cycling between soils Elucidate the role of secondary minerals in regulating soil organic carbon content Communicate scientific findings, and write peer-reviewed scientific papers Profile Must haves: MSc degree in Soil Science, Environmental science or related field Experience with soil sampling and physicochemical laboratory analyses Willingness to travel to and conduct field work in remote alpine catchments Fluent proficiency in English (Toefl C1 or higher) Excellent teamwork and communication for an interdisciplinary and intercultural work environment Ability to work independently and critical thinking Assets: Background in soil biogeochemistry or soil genesis Experience with soil flux measurements using radionuclides Knowledge of German or French is an asset. Workplace Workplace We offer A full-time 4-year PhD position at ETH A friendly, supportive, and interdisciplinary research environment spread across the ETH Earth and Planetary Science and Environmental Systems Science departments An impactful research topic in a rapidly developing field Top of the line laboratory setup Freedom to co-design and develop research ideas beyond the original project setup Placement of position within the ETH domain The position is placed within the ETH Zurich Soil Resources group (Prof. Sebastian Doetterl), in close collaboration with Dr. Katrin Meusburger from WSL who work on the effects of soil degradation and soil development on plant-soil-atmosphere C dynamics. Our laboratories and offices are located in downtown Zurich with greenhouse facilities available also at ETH-s agricultural research station at Eschikon, ZH). chevron_right Working, teaching and research at ETH Zurich We value diversity In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Curious? So are we. Start date will ideally be between 1 April 2025 and 1 June 2025. We look forward to receiving your online application until 31.01.2025 including : Motivation letter (max. 2 pages) describing your interests, goals, and how they relate to the position (in English) Curriculum Vitae including educational history, any publications, awards, etc. (4 pages maximum) (In English) Names and contact details of three references BSc and MSc transcripts (in English or German) Shortlisted applicants will be invited for an interview by 15.02.2025 . We exclusively accept applications submitted through our online application portal. Applications via email or post will not be considered. For more information, please contact sdoetterl@usys.ethz.ch. About ETH Zürich ETH Zurich is one of the world-s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.

Postdoctoral Position - Explore gene expression in healthy and diseased human neuronal networks using electrophysiology and spatial transcriptomics 100%, Basel, fixed-term print Drucken The highly competitive Bio-Engineering Systems for Therapeutics (BEST) postdoc programme , part of the Next-gen Bioengineers initiative, is run jointly by the ETH Zurich and Roche Pharma Research and Early Development. The programme focuses on development of new tools and methods to resolve existing problems and come up with solutions for future challenges in medical translation and therapeutics. Project background Important hallmarks of both neurodevelopmental and neurodegenerative disorders are alterations in gene expression and the electrical properties of neurons. An important objective of this project is to link changes in neuronal functional properties to gene expression at the single cell level. We will address this question by combining single-cell electrophysiology in human neurons, using high-density microelectrode array (HD-MEA) recordings, and spatially resolved single-cell transcriptomic measurements. The developed system will be applied to advanced human cellular models of healthy and mutant neurons. Job description The postdoctoral researcher will be involved in the optimization of cultures of human neurons obtained via transcription factor-mediated reprogramming, the functional characterization of these cells using MEA, optical imaging based on fluorescence in situ hybridization, single-nucleus RNA-sequencing, and the analysis of the obtained data. The candidate will be part of an interdisciplinary team working on related questions at two different locations, the Department of Biosystems Science and Engineering, ETH Zürich, and the Neuroscience and Rare Disease focus area at pRED, Roche. Both Departments are located in the City of Basel. Although the focus of this position is on research, the candidate will also be involved in supervising students and some teaching activities. Profile PhD degree or equivalent in the fields of biology, biotechnology, computational sciences, biomedicine, biomedical engineering, biochemistry, pharmacy, and other related disciplines Interest in getting trained in next generation human model systems and electrophysiology Interest in interdisciplinary research at the campuses of Roche and ETH Zurich in Basel Prior experience with culturing of human iPSC-derived cellular models and MEA electrophysiology is welcome Ability to work independently as well as part of a team, excellent organizational skills and high reliability Fluent oral and written communication skills in English are essential Workplace Workplace We offer Exciting and highly innovative and collaborative research within the framework of Engineering Translational Medicine Co-supervision by ETH Zurich and Roche principal investigators Full access to the facilities and expertise at the campuses of Roche and ETH Zurich Support programme benefits (networking, career development) Regular seminars and joint symposia at ETH Zurich and Roche Fully funded fellowship for 3 years chevron_right Working, teaching and research at ETH Zurich We value diversity In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Curious? So are we. We look forward to receiving your online application with the following documents as a single PDF: A short letter of motivation CV including a list of publications 2 letters of recommendation and/or contact details for referees Brief statement of research interests Copy of your doctoral degree certificate Application deadline: the position is filled on the rolling basis, applications can be submitted until January 6, 2025. Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered. Questions regarding the position should be directed to [Dr. Manuel Schröter] by e-mail [manuel.schroeter@bsse.ethz.ch] and/or [Dr. Marcos R. Costa] by e-mail [marcos.costa@roche.com] (no applications). Further information about the Bio Engineering Laboratory (Electrophysiology & Neuroscience) at D-BSSE ETH Zurich and Neuroscience and Rare Disease focus area Roche pRED can be found on the websites BSSE and Roche Neuroscience. You can find more information about the Next-gen Bioengineers postdoctoral programme on the website. In case of any administrative issues, please contact the Programme office by e-mail [info@next-gen-bioengineers.ethz.ch]. About ETH Zürich ETH Zurich is one of the world-s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.